Menopause triggers a profound shift in skin biology. As oestrogen declines, so does the skin's ability to produce collagen, retain moisture and maintain a healthy barrier. For many women, this is the point at which their skin stops responding in familiar ways, and standard skincare simply is not enough. 

Nimue's MenoDermo Cream with Exosomes has been developed specifically for this. It is an advanced age management treatment cream for perimenopausal, menopausal and postmenopausal skin, drawing on some of the most progressive ingredients in skincare science to support the skin where it needs it most. 

What Makes Exosomes So Significant? 

Exosomes are extracellular vesicles that act as the skin's cellular messaging system, transferring proteins, growth factors and peptides between cells to drive repair and regeneration. Once limited to medicine, their application in advanced skincare is now considered one of the most important developments since retinol. 

MenoDermo Cream uses Centella Reversa, a Phytotech exosome derived from Centella Asiatica (the longevity plant). These plant-based exosomes work on two levels: as delivery vehicles, carrying active compounds deep into the skin, and as signalling agents that directly influence cellular behaviour to promote regeneration and address the markers of cellular ageing. 

The Active Ingredients 

• Centella Reversa (Phytotech Exosome Plant Stem Cells): reduces wrinkles, improves skin texture, firmness, elasticity and pore size through cellular regeneration 

• Sh-Polypeptide-69 (Vegan Skin-Identical Collagen Peptide Complex): a bioidentical recombinant collagen type III that inhibits collagen-degrading enzymes while stimulating new collagen synthesis in the dermis. Produced via precision fermentation; vegan, halal-certified and microbiome-friendly 

• Flax Seed Oil: restores the lipid barrier, deeply hydrates, calms inflammation and improves suppleness 

Niacinamide and Squalane round out the formula, reinforcing the barrier and providing lightweight hydration and antioxidant protection. 

Skin Longevity, Not Just Anti-Ageing

The distinction matters. Anti-ageing is reactive; skin longevity is proactive. MenoDermo Cream works at the root causes of cellular ageing, including collagen degradation, cellular senescence and barrier breakdown, rather than addressing surface-level symptoms after they appear. The goal is to preserve and optimise skin health over time, during the years when the biological case for intervention is strongest. 

The 50ml formula is free from PEGs, silicones, artificial fragrance, lanolin, mineral oils and petrolatum. For use morning and evening on the face and neck, applied over an appropriate Nimue Booster Serum. 

Nimue MenoDermo Cream with Exosomes is available to pros now exclusively through Sweet Squared. Shop here or contact your Partnership Manager for further information. 

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